Transfer RNA

tRNA-Asn), by its anticodon sequence (e.g. tRNA(GUU)), or by both (e.g. tRNA-Asn(GUU) or tRNA Asn GUU ). [19] These two features describe the main function of the tRNA, but do not actually...

Structural basis for sequence-independent substrate selection by eukaryotic wobb

provide sequence-independent interactions that help to select and correctly position the tRNA substrate for catalysis. More generally, our findings provide insights into the evolution of...

tRNAviz: explore and visualize tRNA sequence features

Transfer RNAs (tRNAs) are ubiquitous across the tree of life. Although tRNA structure is highly conserved, there is still significant variation in sequence features between clades, isotypes and eve...

The nucleotide sequence of the structural gene for Escherichia coli tryptophanyl

The complete nucleotide sequence of trpS, the structural gene for Escherichia coli tryptophanyl-tRNA synthetase, was determined using a plasmid carrying the structural gene. From the single open re...

Partition of tRNA synthetases into two classes based on mutually exclusive sets

These proteins differ widely in size and oligomeric state, and have limited sequence... of tRNA. Computational Insight into Substrate-Induced Conformational Changes in Methionyl-tRNA...

Structural basis for methyl-donor–dependent and sequence-specific binding to tRNA substrates by knotted ....

Significance · In bacterial tRNAs with the · 36 · GG · 37 · sequence, where positions 36 and 37 are, respectively, the third letter of the anticodon and 3′ adjacent to the anticodon, the modification of N · 1 · -methylguanosine (m1 G) at position 37 prevents +1 frameshifts on the ribosome. The m1 G37 modification is introduced by the enzyme TrmD, which harbors a deep trefoil knot within the S-adenosyl-L-methionine (AdoMet)-binding site. We determined the crystal structure of the ...

Consider translation of the following mRNA sequence: 5′ AUGCAG... | Channels for Pearson+

Consider translation of the following mRNA sequence: 5′-...AUGCAGAUCCAUGCCUAUUGA...-3′ What is the anticodon triplet sequence of the next tRNA to interact with mRNA?

Consider translation of the following mRNA sequence: 5′ AUGCAG... | Channels for Pearson+

My Course ; Learn ; Exam Prep ; Bookmarks ; Question 1 ; Francis Crick proposed the 'adaptor hypothesis' for the function of tRNA. Why did he choose that description? ; Describe three features of tRNA molecules that lead to their correct charging by tRNA synthetase enzymes. Identify the amino acid carried by tRNAs with the following anticodon sequences. 5′-GAU-3′ ; Identify the amino acid carried by tRNAs with the following anticodon sequences. 5′-AUG-3′ ; Identify the amino acid carried...

The nucleotide sequence of phenylalanine tRNA of Xenopus laevis

The nucleotide sequence of Xenopus laevis phenylalanine tRNA extracted from oocytes was determined to be: pGCCGAAAUAm2GCUCm1AG DDGGGAGAGCm22 G psi psi AGACmUGmAAYA psi C UAAAGm7GDCm5CCUGGT psi CGm1...

Interaction between human tRNA synthetases involves repeated sequence elements.

Aminoacyl-tRNA synthetases (tRNA synthetases) of higher eukaryotes form a multiprotein complex. Sequence elements that are responsible for the protein assembly were searched by using a yeast two-hy...