Efficacy of Pemetrexed-based Chemotherapy in Comparison to Non-Pemetrexed-based Chemotherapy in Advanced, ALK+ Non-Small Cell Lung CancerEfficacy of Pemetrexed-based Chemotherapy in Comparison to N...
Multivariate analyses showed that pemetrexed maintenance chemotherapy was associated with better PFS (hazard ratio, 0.73; 95% confidence interval, 0.15–0.87). Conclusion: Compared to...
To determine its efficacy, we retrospectively evaluated clinical outcomesof pemetrexed-based chemotherapy in patients with ALK+ NSCLC. Materials and Methods: We identified 126 patients with...
Abstract ; Background : First-line therapy for advanced non–small-cell lung cancer (NSCLC) that lacks targetable mutations is platinum-based chemotherapy. Among patients with a tumor proportion score for programmed death ligand 1 (PD-L1) of 50% or greater, pembrolizumab has replaced cytotoxic chemotherapy as the first-line treatment of choice. The addition of pembrolizumab to chemotherapy resulted in significantly higher rates of response and longer progression-free survival than chemotherapy ...
The effect of chemotherapy with cisplatin and pemetrexed for choroidal metastasis of non-squamous cell carcinoma. by Chih-Jen Yang, Ying-Ming Tsai, Ming-Ju Tsai, Hsu-Liang Chang, Ming-Shyan Huang....
The FDA approved amivantamab-vmjw (Rybrevant) plus carboplatin and pemetrexed for the treatment of locally advanced or metastatic non–small cell lung cancer (NSCLC) with EGFR exon 19 deletions or exon 21 L858R substitution mutations. This indication is for patients whose disease has progressed following treatment with an EGFR tyrosine kinase inhibitor (TKI). The phase 3 MARIPOSA-2 trial (NCT04988295) supports this approval.
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Phase 2, randomized, open-label study of ramucirumab in combination with first-line pemetrexed and platinum chemotherapy in patients with nonsquamous, advanced/metastatic non-small cell lung cancer...
Multivariate analyses showed that pemetrexed maintenance chemotherapy was associated with better PFS (hazard ratio, 0.73; 95% confidence interval, 0.15-0.87). Conclusion: Compared to...
English Noun pemetrexed ( uncountable ) A particular drug used in chemotherapy. Synonyms pemetrexed disodium Further reading pemetrexed on Wikipedia. Wikipedia