pemetrexed

English Noun pemetrexed ( uncountable ) A particular drug used in chemotherapy. Synonyms pemetrexed disodium Further reading pemetrexed on Wikipedia. Wikipedia

Pemetrexed - 위키피디아 영어

(verify) Pemetrexed, sold under the brand name Alimta among others, is a chemotherapy medication for the treatment of pleural mesothelioma and non-small cell lung cancer (NSCLC). [2] It is...

Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer | New E

Abstract ; Background : First-line therapy for advanced non–small-cell lung cancer (NSCLC) that lacks targetable mutations is platinum-based chemotherapy. Among patients with a tumor proportion score for programmed death ligand 1 (PD-L1) of 50% or greater, pembrolizumab has replaced cytotoxic chemotherapy as the first-line treatment of choice. The addition of pembrolizumab to chemotherapy resulted in significantly higher rates of response and longer progression-free survival than chemotherapy alone in a phase 2 trial. Methods ...

Gefitinib vs Gefitinib Plus Pemetrexed and Carboplatin Chemotherapy in EGFR-Vari

This randomized clinical trial examines whether adding chemotherapy with pemetrexed and carboplatin to gefitinib improves survival among patients with

Pemetrexed-based first-line chemotherapy had particularly prominent objective re

carboplatin + pemetrexed, cisplatin + docetaxel, etc. Compared with the best supportive care, chemotherapy can improve the 1-year survival rate by 9% [5]. A number of clinical trials from...

Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleura - The Lancet

In patients with advanced pleural mesothelioma, the addition of pembrolizumab to standard platinum–pemetrexed chemotherapy was tolerable and resulted in a significant improvement in overall surviva...

Pemetrexed Continuation Maintenance versus Conventional Platinum-Based Doublet C

Multivariate analyses showed that pemetrexed maintenance chemotherapy was associated with better PFS (hazard ratio, 0.73; 95% confidence interval, 0.15-0.87). Conclusion: Compared to...

Pemetrexed as a Component of First-, Second- and Third-line Chemotherapy in Trea

When third line chemotherapy was needed, pemetrexed 500 $mg/m^2$ and another new chemotherapeutic agent were combined until disease progression. Evaluation of efficacy was conducted after...

Efficacy of Pemetrexed-based Chemotherapy in Comparison to Non-Pemetrexed-based

To determine its efficacy, we retrospectively evaluated clinical outcomesof pemetrexed-based chemotherapy in patients with ALK+ NSCLC. Materials and Methods: We identified 126 patients with...

Study of Pemetrexed-based Chemotherapy for Patients with Locally Advanced or Met

Purpose: This study was conducted to observe the efficacy and safety of pemetrexed based chemotherapy in treating patients with locally advanced or metastatic c