We manufacture recombinant antibodies by cloning antibody genes into high-yield expression vectors and introducing these vectors into hosts. Recombinant antibodies can succeed where other manufacturing methods often fall short. This method isn’t limited by low reproducibility and genetic drift, which lead to variations in the final antibody. Additionally, the generation of antibodies targeting more difficult targets such as toxins, nucleotides, and membrane-bound proteins is possible. ...
As probes to identify materials in laboratories or for use in home-testing kits like those for pregnancy or ovulation. To type tissue and blood for use in transplants. For diagnosis. For disease treatment.
Unraveling what makes a monoclonal antibody difficult-to-express: From intracellular accumulation to incomplete folding and degradation via ERAD. by Sven Mathias, Anna Wippermann, Nadja Raab, Nikol...
We understand the challenges involved in the development of bioanalytical assays to measure levels of large molecule drugs or anti-drug antibodies. You need to design a selective and sensitive assay that works every time, generate translatable and defensible data, and meet your deadlines. We know you need trustworthy critical antibody reagents to do this. Without high quality antibodies you can get stuck developing the method, have to continually requalify new lots, end up feeling insecure about the results, and frustrated about not making prog ...
5-Minute Listen ; "He's anxious that he doesn't want to get sick. He's kind of scared of going back to work because ... he might go through it again," his daughter says. Salvador Perez is right to be worried. It's still not certain that antibodies measured by such a test would protect him from catching the virus again. And if the antibodies are protective, it's unknown how strong that protection might be or how long it might last. There are also questions about the reliability of many antibody tests being sold. ...
What is an ANA (Antinuclear Antibody) Test? An ANA test is a blood test that looks for... Antibodies are proteins that your immune system makes to fight foreign substances, such as viruses...
Immunoglobulin M: Your body makes IgM antibodies when you are first infected with new... Another way to do this test is with a sample of what’s called cerebrospinal fluid (CSF). CSF...
Monoclonal antibodies have been a breakthrough treatment for cancer and other diseases. Now doctors are turning to them in the fight against COVID-19. Find out what this therapy is, how it works, a...
Antibodies are Y-shaped proteins that the body produces when it detects antigens. Antibodies are produced by immune cells... Antibodies (immunoglobins) are Y-shaped proteins produced by B...
Shaped like a 'Y', antibodies contain a highly-variable region in their fork, which allows... One involves a domino-effect of changes among what's known as a complement system of signalling...