Viral vectors are modified viruses designed to deliver genetic material into cells. This process can be performed inside an organism or in cell culture. Viral vectors have widespread applications in basic research, agriculture, and medicine. Viruses have evolved specialized molecular mecha...
A viral vector vaccine is a vaccine that uses a viral vector to deliver genetic material (DNA) that can be transcribed by the recipient's host cells as mRNA coding for a desired protein, or antigen, to elicit an immune response. As of April 2021, six viral vector vaccines, four COVID-19 va...
Related Technical Articles ; Adenovirus Vaccine Manufacturing Process · This technical article breaks down the adenovirus vaccine manufacturing process and provides a case study on developing an accelerated and cost-effective single-use adenoviral vector vaccine. Cost Modeling Vaccine Manufacturing: Estimate Production Costs for mRNA and other Vaccine Modalities · A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understa ...
바이럴 벡터(Viral Vector)는 DNA나 RNA와 같은 유전물질을 세포에 주입하기 위해 개발된 운반체다. 유전자치료제의 핵심기술로, 독성이 거의 없는 바이러스의 껍데기에 치료 유전자를 넣어 암세포나 질병세포에 전달한다.
바이러스 벡터 백신 (viral vector) 유전자를 세포에 전달하는 운반체인 벡터 에 치료유전자를 삽입시켜서 만드는 백신. 바이러스성 벡터로는 주로 아데노바이러스와 레트로바이러스가 이용된다. 폴리머나...
Millipore® CTDMO Services offer viral vector development and manufacturing for advancing cell and gene therapies.
To review the viral vector-based gene therapy landscape, we focus on these three highly regarded vector platforms and describe mechanisms of action and their roles in treating human...
생 벡터 백신은 면역 반응을 자극하는 항원 일부를 전달하는 아데노바이러스와 같은 악독화 또는 무해한 미생물을 사용합니다. 벡터화된 백신은 잠재적으로 세포 간접 면역성을 가능하게 하며, 이는 AIDS, 말라리아, 암 등의 복잡한 질병에 필수적입니다. 백신 벡터 제조 공정은 대부분 템플릿화되었지만 다양한 특성의 여러 바이러스가 사용됨에 따라 어려움이 발생할 수 있습니...
A transfection-based solution to viral vector production using a suspension cell line, chemically defined medium, and a process with proven performance at scale.
Viral vector purification processes have historically been based on systems used for monoclonal antibodies, which are not designed to deliver the necessary level of recovery. The...