Screen with speed · Twist has developed an optimized in vivo discovery workflow based on immunized camelids tailored for cell surface targets. We leverage an industry-leading, Beacon-based, single B cell screening platform, enabling the rapid identification of binders with required activities and/or cross-reactivity in 1 day. Never miss a hit · We screen IgG2/3-secreting alpaca B cells for specificity and function using a high-resolution screening cascade that includes up to four on-cell ass...
VHH antibody fragments from the library were expressed intracellularly, and a number of antibodies were shown to possess function-modifying intracellular activity in a luciferase-based Wnt...
Overview ; A single chain fragment variable (scFv) is a type of recombinant antibody. It is approximately 25 kDa and consists of the variable regions of the heavy (VH) and light (VL) chains of an antibody, which are connected by a flexible peptide linker (such as G4S linker or whitlow/218 linker). scFvs have several advantages, including their small molecular weight, strong penetration, and high specificity1 . They play crucial roles in targeted therapy, imaging diagnosis, and biological detecti...
Overview ; VHH nanobody is a promising tool in therapeutics and immunodiagnostics applications, such as developing recombinant antibody drugs and CAR-T therapy. GenScript has developed a series of rabbit monoclonal (MonoRab™) anti-VHH antibodies to facilitate your research of VHHs. What is VHH? · Members of the Camelidae family, including llamas, alpacas, and camels, produce two types of IgG antibodies. One type is the conventional IgG1 (MW150 kDa) with two heavy chains and two light chains....
Alpaca Anti-Rabbit IgG(Fcγ) VHH Nano secondary antibody,freeze-dried powder, Sigma-Aldrich-high affinity and sensitivity.Validated in WB, Elisa.
Alpaca Anti-Mouse IgG2a(Fcγ) VHH Nano secondary antibody,freeze-dried powder, Sigma-Aldrich-high affinity and sensitivity.Validated in WB, Elisa.
Alpaca Anti-Mouse IgG(Fcγ) HRP VHH Nano secondary antibody,freeze-dried powder, Sigma-Aldrich-high affinity and sensitivity.Validated in WB, Elisa.
Alpaca Anti-Goat IgG(Fcγ) VHH Nano secondary antibody,freeze-dried powder, Sigma-Aldrich-high affinity and sensitivity.Validated in WB, Elisa.
Create and explore large, diverse naïve VHH antibody libraries for therapeutic development
Alpaca Anti-Goat IgG(Fcγ) HRP VHH Nano secondary antibody,freeze-dried powder, Sigma-Aldrich-high affinity and sensitivity.Validated in WB, Elisa.