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Abstract ; Background/Aims To describe the role of ustekinumab in inducing remission and endoscopic healing in anti-tumor necrosis factor α nonresponsive pediatric ulcerative colitis patients at a tertiary care inflammatory bowel disease center. Methods A retrospective chart review was performed on patients with ulcerative colitis receiving ustekinumab. Primary outcome was steroidfree clinical remission at follow-up. Secondary outcomes were biochemical remission and endoscopic healing. ...
The incidence of lactose malabsorption was investigated in 85 patients with ulcerative colitis and 71 patients with Crohn's disease by means of lactose tolerance tests and disaccharidase determinat...
Introduction: Ulcerative colitis is an idiopathic, chronic inflammatory disease of the colonic mucosa. Its clinical course is unpredictable, marked by alternating periods of exacerbation and remiss...
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021) ; 자료유형 : article, Content Provider : Directory of Open Access Journals, 초록 : Abstract Background Fecal biomarkers are considered to be useful surrogate markers for endoscopic activity. Given the mechanisms of fecal biomarkers, we hypothesized that the extent of ulcerative colitis (UC; pancolitis, left-sided colitis, and proctitis) could affect the usefulness of fecal biomarkers for assessing endoscopic and clinical disease activity; however, few studies have evaluated the utility of ...
Neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate serum marker of mucosal healing in ulcerative colitis. by Magali de Bruyn, Ingrid Arijs, Willem-Ja...
Ulcerative colitis (UC) is a chronic, relapsing, and remitting inflammatory disease involving the large intestine (colon). Treatment seeks to break recurrent inflammation episodes by inducing and m...
The early identification of patients with ulcerative colitis who have an increased risk of colorectal cancer would be useful for clinicians. In this Review, the authors discuss the most promising p...
The exact cause of ulcerative colitis is not known. It is, however, considered to be an autoimmune disease.
Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia. by Jacob T Bjerrum, Ole H Nielsen, Lene B Riis, Valerie Pittet, Christoph Mueller, Gerhard R...