1 COVID-19 8 References Medical uses [edit] It is used as a second line treatment to manage symptoms of rheumatoid arthritis after treatment with a disease-modifying antirheumatic drug...
06 g·mol −1 (what is this?) (verify) Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic...
Abstract Purpose: Current and investigational treatments of rheumatoid arthritis (RA) are... with a combination of drugs or biological agents may be warranted for the effective treatment of RA.
It happens when the immune system doesn’t work properly and attacks the lining of the joints, called the synovium. The disease commonly affects the hands, knees or ankles, and usually the same joint on both sides of the body, such as both hands or both knees. But sometimes RA causes problems in other parts of the body as well, such as the eyes, heart and circulatory system and/or the lungs. For unknown reasons, more women than men get RA, and it usually deve ...
The precise mechanism of action of folate antagonist MTX in the treatment of rheumatoid arthritis (RA) is unclear, although it is thought that MTX prevents de novo pyrimidine and purine...
Thirty patients with classical or definite rheumatoid arthritis were randomly divided into two groups of fifteen patients each of similar age, sex, duration and severity of disease, and medical tre...
Rheumatoid Arthritis (RA) is a chronic inflammatory disease characterized by a heterogeneous clinical response to the different treatments. Some patients are difficult to treat and do not reach the...
In patients with active rheumatoid arthritis who were receiving methotrexate, treatment with CTLA4Ig significantly improved the signs and symptoms of rheumatoid arthritis and the health-related qua...
Abstract ; Rheumatoid arthritis (RA) 3 is a chronic inflammatory disease characterized by synovial hyperplasia with massive infiltration of inflammatory cells in the affected joints. This hyperplasia leads to degeneration of cartilage, erosion of bone, and ultimately functional loss of joints. Although the etiology of RA remains elusive, T cells recognizing unknown autoantigens have been proposed to initiate inflammation in synovial tissues. This mechanism is followed by local recruitment of leu...
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic joint inflammation. Learn about causes, symptoms, stages, treatments, medications, prognosis, complications, and prevention.