이러한 비정상적인 형질세포를 골수종세포(myeloma cell)라고 부르며, 이는 종양을 만들고 뼈를 녹여... 벨케이드(velcade)), 탈리도마이드(thalidomide), 레날리도마이드(lenalidomide) 등이 있다. 그 외에도 임상 시험을...
Abstract ; Background : Patients with myeloma who relapse after high-dose chemotherapy have few therapeutic options. Since increased bone marrow vascularity imparts a poor prognosis in myeloma, we evaluated the efficacy of thalidomide, which has antiangiogenic properties, in patients with refractory disease. Methods : Eighty-four previously treated patients with refractory myeloma (76 with a relapse after high-dose chemotherapy) received oral thalidomide as a single agent for a median of 80 days...
Abstract. Multiple myeloma is a clonal plasma cell malignancy that accounts for slightly more than 10% of all hematologic cancers. In this paper, we present a h
서론 ; 다발골수종은 골수의 형질세포가 악성 변화되어 발생하는 대표적인 혈액암으로, 골수내 비정상적인 형질세포의 증식은 빈혈, 고칼슘혈증, 신기능 부전, 그리고 골용해성병변과 같은 특징적인 임상 증상을 유발한다. 발생률은 나이에 따라 증가하는 경향을 보이며, 진단 시 중앙연령은 70세이고, 여성보다는 남성에서 더 흔하게 발생하는 것으로 보고되고 있다[1]. 국내 다발...
Multiple myeloma is a type of cancer that affects plasma cells. Learn about multiple myeloma symptoms, diagnosis, risk factors, and treatment.
Thalomid (Thalidomide) is less commonly prescribed for multiple myeloma, but may be a good alternative for patients with low blood cell counts.
다발성 골수종(multiple myeloma, MM)은 혈액 내 백혈구의 일종인 형질 세포(plasma cell)가 비정상적으로 분화, 증식되어 발생하는 혈액 종양이다 1. 주 증상증식된 종양 세포가 파골 세포 활성인자(osteoclast-activating factor, OAF)의 생성을 촉진함으로써 용해성 골병변이 발생한다. 다발성 골수종 환자들에...
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English Noun iberdomide ( uncountable ) ( pharmacology ) A derivative of thalidomide used experimentally for the treatment of multiple myeloma and systemic lupus erythematosus.
Lenalidomide , sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). For multiple myeloma, it is a first line treatment, and is given with dexamethasone. It is taken by mouth. Common side ef...