Rapamycin potently inhibits downstream signaling from the target of rapamycin (TOR) proteins. These evolutionarily conserved protein kinases coordinate the balance between protein synthesis and pro...
The TOR (target of rapamycin) proteins play important roles in nutrient signaling in eukaryotic cells. Rapamycin treatment induces a state reminiscent of the nutrient starvation response, often res...
Abstract. The mammalian target of rapamycin (mTOR) has emerged as an important cancer therapeutic target. Rapamycin and its derivatives that specifically
Mammalian target of rapamycin (mTOR) signal was activated in the aortic wall of CRF rats. As expected, oral rapamycin administration significantly reduced VC by inhibiting mTOR in rats with...
Mechanistic target of rapamycin (Mtor) is required for embryonic inner cell mass proliferation during early development. However, Mtor expression levels are very low in the mouse heart during embry...
The IUPHAR/BPS Guide to Pharmacology. mechanistic target of rapamycin kinase - FRAP subfamily. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of dru...
The rationale of targeting mammalian target of rapamycin for ischemic stroke. by Zhao Zhong Chong, Qingqiang Yao, Hui-Hua Li. Cellular signalling. Read more related scholarly scientific articles an...
Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways. by Delphine Rispal, Sandra Eltschinger, Michael Stahl, Stefania Vaga, Bernd Bodenmiller, Yann Abrah...
TOR (Target Of Rapamycin) is a highly conserved protein kinase that is important in both fundamental and clinical biology. In fundamental biology, TOR is a nutrient-sensitive, central controller of...
Abstract In cucumber production, delaying leaf senescence is crucial for improving cucumber yield and quality. Target of rapamycin (TOR) is a highly conserved serine/threonine protein kinase in euk...