In chemistry, solid-phase synthesis is a method in which molecules are covalently bound on a solid support material and synthesised step-by-step in a single reaction vessel utilising selective protecting group chemistry. Benefits compared with normal synthesis in a liquid state include: Hi...
Learn about solid phase peptide synthesis (SPPS). A technique used for producing peptides efficiently.
Read the latest Research articles in Solid-phase synthesis from Nature Medicine
Read the latest Research articles in Solid-phase synthesis from Nature Chemistry
Read the latest Research articles in Solid-phase synthesis from Experimental & Molecular Medicine
In solid-phase synthesis, the compounds being made are attached to insoluble, functionalized, polymeric material allowing them to be readily separated from excess reagents, soluble reaction by-prod...
Peptides are manufactured using solid phase FMOC or BOC chemistry methodologies on a PEG-Polystyrene support resin. Upon synthesis completion, side chain protecting groups are removed and the pepti...
Due to the nature of solid-phase synthesis, the number and order of the side chains and additional units can be precisely defined. The method proved to be versatile for the generation of...
4748 Solid Phase Synthesis Article Solid Phase Synthesis Bruce Merrifield Authors Info & Affiliations Science 18 Apr 1986 Vol 232, Issue 4748 pp. 341-347 DOI: 10.1126/science.3961484 CHECK...
Read the latest Research articles in Solid-phase synthesis from Scientific Reports