The FDA warning, released again on 8 June 2011, suggested that high-dose "simvastatin should be used only in patients who have been taking this dose for 12 months or more without evidence...
Objectives: ; Identify the mechanism of action of simvastatin. ; Review the indications for using simvastatin in lipid control. ; Explain the adverse event profile of simvastatin and how it compares with other statin medications.
Phenotype, Implications ; SLCO1B1 increased function, Typical myopathy risk and statin exposure ; SLCO1B1 normal function, Typical myopathy risk and statin exposure ; SLCO1B1 decreased (or possible decreased) function, Increased simvastatin acid exposure as compared with normal function; increased risk of myopathy
Recent Examples on the Web ; Simvastatin: The dosage of amlodipine needs to be reduced when used in combination with simvastatin, a cholesterol medication (brand name Zocor). Megan Nunn, Verywell Health, 19 Sep. 2024 ; Patients can obtain low-dose simvastatin without a prescription, but the medications are placed behind the pharmacy counter and distributed after a pharmacist’s consultation. Joshua Cohen, Forbes, 2 Mar. 2024 ; One is called simvastatin, used to manage high cholesterol. Dina Fin...
High dose simvastatin and rosuvastatin impair cognitive abilities of healthy rats via decreasing hippocampal neurotrophins and irisin. by Nilsel Okudan, Muaz Belviranli. Brain research bulletin. Re...
주목할만한 약물 상호 작용에는 에리스로마이신과 심바스타틴이 포함되어 심바스타틴 수치가 증가하고 횡문근융해증의 가능성이 있습니다.
High dose simvastatin and rosuvastatin impair cognitive abilities of healthy rats via decreasing hippocampal neurotrophins and irisin. by Nilsel Okudan, Muaz Belviranli. Brain research bulletin. Re...
Safety Announcement · Additional Information for Patients · Additional Information for Healthcare Professionals · Data Summary · Simvastatin Dose Limitations · Safety Announcement
OVERVIEW ; Introduction ; Background ; Hepatotoxicity ; Mechanism of Injury ; Outcome and Management
About simvastatin · Who can and cannot take it · How and when to take it · Side effects · Pregnancy, breastfeeding and fertility · Taking simvastatin with other medicines and herbal supplements · Common questions