Phorbol is a natural, plant-derived organic compound. It is a member of the tigliane family of diterpenes. Phorbol was first isolated in 1934 as the hydrolysis product of croton oil, which is derived from the seeds of the purging croton, Croton tiglium . The structure of phorbol was determ...
Phorbol esters are a class of chemical compounds found in a variety of plants, particularly in the families Euphorbiaceae and Thymelaeaceae. Chemically, they are ester derivatives of the tetracyclic diterpenoid phorbol. Biological activity Protein kinase C (PKC) is a phorbol ester receptor...
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The effect of phorbol esters on the extent of phosphorylation of receptors for insulin and somatomedin C (insulin-like growth factor I) was studied in intact IM-9 cells that were labeled by incubat...
Download scientific diagram | Occurring of phorbol esters. from publication: Elimination of toxic phorbol esters in Jatropha curcas seed oil by adsorption technique | Nowadays Jatropha curcas is on...
The phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA) (10 nM) produce a marked reduction in the growth, measured by thymidine uptake, of MCF-7 cells in full growth medium, but had...
phorbol ester [화합물] 구조정보 화합물 이름 phorbol ester CAS 번호 16561-29-8 화학식 C 36 H 56 O 8 분자량 616.8336 CNMR 65.70(C2), 76.10(C3), 36.10(C4), 39.40(C5), 132.70(C6), 151.42(C7), 62.54(C8), H...
Phorbol esters are the tetracyclic diterpenoids generally known for their tumor promoting activity. The phorbol esters mimic the action of diacyl glycerol (DAG), activator of protein kinase C, whic...
PMA Phorbol myristate acetate - NF-kB Activator PMA (Phorbol myristate acetate) 또는 TPA (12-O... PMA는 가장 흔하고 강력한 phorbol ester이며, nM 농도에서 활성을 가지며, dose-dependent...
C phorbol ester receptors. They were the first phorbol ester receptors to be discovered... the phorbol ester tumor promoters. The name stems from their resemblance to the "chimera." Types...