Summary Redirection Notice This page will redirect to https://www.cancerimagingarchive.net/collection/anti-pd-1_melanoma/ in about 5 seconds. This collection includes 47 melanoma cases...
DOI: 10.7937/tcia.2019.1ae0qtcu | Data Citation Required| Location : Skin, Species : Human, Subjects : 47, Data Types : CT, MR, PT, Cancer Types : Melanoma, Size : 98.41GB, Status : Limited, Complete, Updated : 2018/07/30
SummaryThis study evaluated the expression of PD‐L1 in immunotherapy‐naïve metastatic melanoma patients to determine longitudinal intrapatient concordance and correlate PD‐L1 status with clinicopat...
Therapeutic antibodies targeting programmed cell death 1 (PD-1) activate tumor-specific immunity and have shown remarkable efficacy in the treatment of melanoma. Yet, little is known about tumor ce...
Immunologic responses to anti-PD-1 therapy in melanoma patients occur rapidly with pharmacodynamic T cell responses detectable in blood by 3 weeks. It is unclear, however, whether these early blood...
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Combination anti-cytotoxic T lymphocyte antigen 4 (CTLA-4) and anti-programmed cell death protein 1 (PD-1) therapy promotes antitumor immunity and provides superior benefit to patients with advance...
BACKGROUNDTherapeutic antibodies against programmed cell death receptor 1 (PD‐1) are considered front‐line therapy in metastatic melanoma. The efficacy of PD‐1 blockade for patients with biological...
Knockdown of FTO sensitizes melanoma cells to interferon gamma (IFNγ) and sensitizes melanoma to anti-PD-1 treatment in mice, depending on adaptive immunity. Our findings demonstrate a...
Melanoma is a carcinoma known to evade the host immune defenses via the downregulation of the immune response. One of the molecules involved in this mechanism is programmed cell death ligand 1 (PD-...