[2] While the cause of rheumatoid arthritis is not clear, it is believed to involve a... 3 Negative findings 3 Pathophysiology 3.1 Non-specific inflammation 3.2 Amplification in the...
Autism, Developmental Coordination Disorder, Spina Bifida, Juvenile Idiopathic Arthritis and Haemophilia ; An Overview of Paediatric Conditions Programme ; Cerebral Palsy General Assessment and Interventions
Rheumatoid arthritis (RA) is a common autoimmune systemic inflammatory disease affecting approximately 1% of the worldwide population. The interaction of genetic and environmental factors results i...
The most common sites of rheumatoid arthritis (RA) are the metatarsophalangeal joints, followed by the metacarpophalangeal joints and the cervical spine (ankylosing spondylitis, rheumatoid spondyli...
The results confirm the proinflammatory potential of adiponectin and support the idea that adiponectin influences rheumatoid arthritis bone remodelling through alterations in osteoblast and osteocl...
RASFs in the pre-inflammatory phase of rheumatoid arthritis ; From a functional and therapeutic point of view, the preclinical stage of RA is of great interest. One of the most challenging goals in RASF research is to determine the specific role that these cells play in the early phase of the disease. As outlined below, it appears that, before clinical signs of RA become evident, activation of the innate immune system leads to a distinct upregulation of effector molecules in RASFs. Potential triggers for this early activation are infectious as ...
insights into genetics and aetiology, pathophysiology, epidemiology, assessment, therapeutic agents, and treatment strategies together with unmet needs of patients with rheumatoid arthritis.
The aetiology of systemic, autoimmune, chronic inflammatory diseases--such as rheumatoid arthritis--is not known, and their pathogenesis is complex and multifactorial. However, progress in the char...
Rheumatoid arthritis (RA) is a chronic inflammatory illness that primarily affects the joints. It is associated with symptoms of fatigue, pain, and sleep disturbances that can overlap with or mimic...
Juvenile rheumatoid arthritis (JRA) has a complex, poorly characterized pathophysiology. Modeling of transcriptosome behavior in pathologic specimens using microarrays allows molecular dissection o...