Articles ; Unraveling a Recurrent Wrong Drug-Wrong Route Error—Tranexamic Acid in Place of Bupivacaine: A Multistakeholder Approach to Addressing this Important Patient Safety Issue ; Intraoperative Hypotension: A Public Safety Announcement for Anesthesia Professionals ; An Evolving Framework for Using Big Data Tools and Machine Learning to Enhance Perioperative Quality Improvement, Research, and Patient Safety ; Opioid-Induced Respiratory Depression—Pediatric Considerations
The Opioid Epidemic: Origins, Current State and Potential Solutions ; The Opioid Epidemic: What Everyone Needs to Know ; Poppy Seed: Revealing the Roots of the Opioid Epidemic
A Stanford research team finds that ketamine's ability to quickly relieve depression may depend on activating the brain's opioid system. The finding raises new questions about the drug's safety.
Opioid treatment of pain is generally safe with 0.5% or less events from respiratory depression. However, fatalities are regularly reported. The only treatment currently available to reverse opioid...
Keywords: Delta opioid receptor (DOR); Depression; Kappa opioid receptor (KOR); Mu opioid receptor (MOR); Nociceptin opioid receptor (NOP); Opioid system.
In this sample of veterans with no recent (24-month) history of depression or opioid analgesic use, the risk of development of depression increased as the duration of opioid analgesic exposure incr...
Importance of the correct diagnosis of opioid-induced respiratory depression in adult cancer patients and titration of naloxone. by Jason Boland, Elaine Boland, David Brooks. Clinical medicine (Lon...
The analgesic utility of opioid-based drugs is limited by the life-threatening risk of respiratory depression. Opioid-induced respiratory depression (OIRD), mediated by the μ-opioid receptor (MOR),...
Opioids are effective analgesics, but they can have harmful adverse effects, such as addiction and potentially fatal respiratory depression. Naloxone is currently the only available treatment for r...
Schwab-Reese Purpose To assess the relationship between state-level depression and opioid overdose deaths between 2011 and 2015 in the United States. Methods We assessed the association...