Effective treatment of tuberculosis (TB), including its drug-resistant forms, relies on the use of several medicines administered in combination for an adequate duration. For many years, conventional treatment regimens for rifampicin-resistant TB (RR-TB) and multidrug-resistant TB (MDR-TB, defined as TB that is resistant to both rifampicin and isoniazid), collectively referred to as MDR/RR-TB, were lengthy and arduous, and included painful injectable medicines. Compared with treatments for drug-susceptible forms of TB, the duration of treatment ...
This comprehensive update of the now classic text applies the most current findings across disciplines to the treatment of pathogenic human stress arousal. New and revised chapters bring together t...
서명 / 저자 : Alzheimer's disease : new treatment strategies / edited by Zaven S. Khachaturian, John P. Blass. 저자명 : Khachaturian, Zaven S. ; Blass, John P. 발행사항 : New York : M. Dekker, 1992. 상세정보 : 네이버 상세보기
New paradigms for treatment-resistant depression. by Carlos Zarate, Ronald S Duman, Guosong Liu, Simone Sartori, Jorge Quiroz, Harald Murck. Annals of the New York Academy of Sciences. Read more re...
Depression is prevalent and costly, but despite effective treatments, is often untreated. Recent efforts to improve depression care have focused on primary
New celecoxib multiparticulate systems to improve glioblastoma treatment. by M Vera, E Barcia, S Negro, P Marcianes, L García-García, K Slowing, A Fernández-Carballido. International journal of pha...
Abstract ; Background : Among patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with acute ischemic stroke with a small infarct core, a proximal intracranial arterial occlusion, and moderate-to-good collateral circulation. Methods : We randomly assigned participants...
Request PDF | New Trial(s) on Antiedema Treatment in Stroke? | To the Editor: We read with interest the Controversies in Stroke on steroids,1 and appreciated both Dr Norris’ and Dr Poungvarin’s pap...
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure. by C R Taylor, J R Baird, K J Blackburn, D Cambridge, J W Constantine, M S Ghaly, M L Hayden, H M McIlh...
Absorption : Bioavailability: ~48% T · max: ~20–40 min, Distribution : Volume: ~709 l (based on intravenous administration) · Protein binding: ~43–45%, Metabolism : Main initial metabolite, nor-esketamine (less active than parent drug) Cytochrome P450 iso-enzyme mediated-metabolism: 2D6 and 3A4, with some input from 2C9 and 2C19, Elimination : Mean terminal half-life: ~7–12 h · Urinary: metabolites, 78% · Faeces: metabolites, <2%