FDA Opens the Door to Clinical Use of LSD

March 26, 2024 -- If you think of LSD as a dangerous illegal drug without any legitimate medical uses, think again. LSD is still illegal, but recent studies show that this powerful compound is not usually dangerous if taken under controlled circumstances and that it has the potential to help some people with serious mental conditions. The FDA recently designated a form of LSD as a breakthrough therapy to treat generalized anxiety disorder. This decision was based partly on a rigorously designed drug trial in which about half of the patients on ...

FDA Grants Breakthrough Therapy Designation to LSD-Based Treatment for Generalized Anxiety Disorder - Dru....

About MMED008 ; Trial Name: A Dose-Finding Study of MM-120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms ; ClinicalTrials.gov Identifier: NCT05407064 ; Sponsor: Mind Medicine ; Summary: This is a Phase 2, multi-center, randomized, double-blind, parallel-group, dose-finding study to assess the effect of 4 doses of MM-120 (25, 50, 100 or 200 μg freebase-equivalent) for the treatment of anxiety symptoms in subjects diagnosed with generalized anxiety disorder (GAD).

LSD Returns--For Psychotherapeutics

Albert Hofmann, the discoverer of LSD, lambasted the countercultural movement for marginalizing a chemical that he asserted had potential benefits as an invaluable supplement to psychotherapy and spiritual practices such as meditation. “This joy at having fathered LSD was tarnished after more than ten years of uninterrupted scientific research and medicinal use when LSD was swept up in the huge wave of an inebriant mania that began to spread over the Western world, above all the United States, at the end of the 1950s,” Hofmann groused in hi ...

What Is A Lethal Dose Of LSD? - Addiction Resource

Medically Reviewed by · Johnelle Smith, M.D. on July 13, 2021 ; Written by · Percival Fisher, Jr., MBA, LCSW-C, LICSW, LCSW, BCD, CCM

LSD-Like Drug Wins FDA 'Breakthrough Therapy' Status For Treatment Of Generalize

A study last year, however, found that both LSD and psilocybin could potentially be used as powerful treatments for pain without the dwindling efficacy over time associated with opioid...

Pharmaceuticals | Free Full-Text | Lysergic Acid Diethylamide, Psilocybin and Dimethyltryptamine in Depre....

diethylamide (LSD), psilocybin and dimethyltryptamine (DMT)... The aim of this study was to evaluate the efficiency of LSD... Keywords: lysergic acid diethylamide (LSD); psilocybin;...

FDA Grants Breakthrough Therapy Status To LSD Drug To Treat Anxiety

drug LSD as a treatment for anxiety. The drug, a form of LSD (lysergide d-tartrate)... effective treatments for GAD, especially in patients who do not respond to or tolerate currently...

LSD-assisted therapy induces rapid and lasting reductions in anxiety and depress

LSD-assisted therapy could provide benefits to patients... LSD-assisted therapy involves the controlled administration of... Although LSD is best known as a recreational drug, some research...

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Consequently, there is an urgent need to develop new treatments targeting molecular pathways enriched in lethal prostate cancer. Lysine-specific demethylase 1 (LSD1) is a histone demethylase and an important regulator of gene expression. Here, we show that LSD1 promotes the survival of prostate cancer cells, including those that are castration-resistant, independently of its demethylase function and of the AR. Importantly, this effect is explained in part by activation of a lethal prostate cance...

Psychedelic drug LSD may be effective in anxiety treatment

future treatments, Dr. Gobbi explained to MNT, “One small published clinical trial has suggested that LSD may alleviate anxiety in life-threatened patients. These animal data can support...