The life span of erythrocytes in pregnant rats is shorter than in nonpregnant ones. A similar shift in the age distribution of pregnant rat and pregnant human erythrocytes is probably associated wi...
The basic question which remains unanswered is whether immunologically competent cells in the chimera originate from the donor, the host, or a combination of both. Erythrocyte life-span...
Survival data are reported for 572 male non-breeding Fischer rats, representing offspring from brother-sister matings, maintained at a constant temperature and humidity, exposed to twelve hours of...
Consider that living creatures, including mice and men, are assemblies of biological systems, all working together at different levels — molecular, subcellular, cellular, tissue, and organ. Life span is determined by the first biological system to fail beyond compensation. This has a critical implication for experimental design when studying basic mechanisms of aging. We define an aging mechanism as one that coordinates the expression of diverse biomarkers of aging or that couples biomarkers o...
Life span (in days) was recorded for each rat. Mature body weight of male and female progeny of dams fed restricted protein... gestation of a magnitude large enough to reduce pup birth...
BackgroundIn a previous study conducted at the Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (CMCRC/ERF), we demonstrated for the first time that aspartame (APM) is a m...
mean life span of the most long-lived 10% of a given cohort. By another definition, however... The records (in years) are these: for common house mouse, 4 [29] for Brown rat, 3.8 [30] for...
Abstract. 1. A method is described for the isolation of rat platelets. The method gives high yields of platelets with negligible white and red cell contaminatio
At a laboratory outside San Francisco, money from the founders of Google maintains a large number of naked mole rats. The hairless rodents require exacting, expensive conditions to thrive: they liv...
By analyzing 15,000 samples from 348 mammalian species, we derive DNA methylation (DNAm) predictors of maximum life span (R = 0.89), gestation time (R = 0.96), and age at sexual maturity (R = 0.85)...