You may be worried about phenylalanine because of a warning on diet soda. Find out why the warning is there.
Phenylketonuria (PKU) is an inherited disorder that increases the levels of phenylalanine in the blood. Explore symptoms, inheritance, genetics of this condition.
Phenylalanine is one of the common amino acids in proteins, and a nutritionally essential amino acid. Phenylalanine occurs naturally in...
Phenylketonuria is an inherited disorder of metabolism that causes an increase in the blood of a chemical known as phenylalanine.
p-Cyano-l-phenylalanine (pCNPhe) is an unnatural amino acid used in optical probes for imaging proteins. It was introduced in a 1994 world patent application by Richard T. Dean and co-inventors at Diatide (Londonderry, NH), who used it as a chelator for the radionuclide technetium-99m in a procedure for detecting blood clots (thrombi). The patent application was followed by a 1996 Journal of Medicinal Chemistry article. Since that finding, pCNPhe showed its versatility in other applications. In a 2009 report, Daniel P. Raleigh, Isaac Carrico, a ...
It is caused by harmful genetic changes in the PAH gene. Phenylalanine is found in proteins and other certain foods. If individuals with PAH deficiency do not get treatment, phenylalanine can accumulate to harmful levels, which can cause irreversible intell ...
1 It is caused by a defect in the gene that helps create the enzyme needed to break down phenylalanine.1 If left untreated or poorly managed, phenylalanine – an essential amino acid found in all proteins and most foods – can build up to harmful levels in the body. This causes severe and irreversible disabilities, such as permanent intellectual disability, seizures, delayed development, memory loss, and behavioral and emotional ...
About one in 15,000 babies is born with PKU in the United States. ; PKU leads to a build-up of the amino acid phenylalanine, which is toxic to the nervous system. ; Without treatment, PKU can cause intellectual disabilities.
Phenylalanine hydroxylase (PAH) deficiency results in intolerance to the dietary intake of the essential amino acid phenylalanine and produces a spectrum of disorders. The risk of adverse outcome v...
Phenylalanine hydroxylase deficiency is an autosomal recessive disorder that results in intolerance to the dietary intake of the essential amino acid phenylalanine. It occurs in approximately 1:15,...