The interleukin-1 receptor antagonist ( IL-1RA ) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially called the IL-1 inhibitor and was discovered separately in 1984 by two independent laboratories. IL-1RA is an agent that binds non-productively to the cell surfac...
"Interleukin 1 receptor antagonist. A new member of the interleukin 1 family". J. Clin. Invest. 88 (5): 1445–51. doi:10.1172/JCI115453. PMC 295645 . PMID 1834696. ^ Wesche H, Korherr C...
Deficiency of the interleukin-1–receptor antagonist ( DIRA ) is an autosomal recessive, genetic autoinflammatory syndrome resulting from mutations in IL1RN , the gene encoding the interleukin 1 receptor antagonist. Symptoms and signs DIRA displays a constellation of serious symptoms which...
The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear.We evaluated tocilizumab and sarilumab in an ongoing international,...
Interleukin-1 receptor antagonist displays intrinsic agonist activity on rat gastric fundus motility in vitro. by P Montuschi, G Tringali, A Mirtella, L Parente, P Preziosi, P Navarra. European jou...
Complete information for IL1RN gene (Protein Coding), Interleukin 1 Receptor Antagonist, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Co...
"receptor antagonist"을 한국어로 번역 ; 길항작용 은 "receptor antagonist"을 한국어로 번역한 것입니다. 샘플 번역 문장: Human interleukin-1 receptor antagonist - hybrid fc fusion protein ↔ 인간 인터루킨-1 수용체 길항제-하이브리드 Fc 융합단백질
The protein binds to the interleukin-1 receptor but has no interleukin-1-like activity, even at very high concentrations, and is therefore a pure receptor antagonist. Study on the...
IL-1ra is the first described naturally occurring receptor antagonist of any cytokine or hormone-like molecule. IL-1ra is a member of the IL-1 family by three criteria: amino acid sequence homology...
human Interleukin-1 receptor antagonist protein; syn. N2-l-methionyl-interleukin 1 receptor antagonist (human isoform x reduced) CAS Number 143090-92-0 DrugBank DB00026 ChemSpider none UNII...