The hypoxia-selective cytotoxin NLCQ-1 (NSC 709257) controls metastatic disease when used as an adjuvant to radiotherapy SJ Lunt 1,5,7 , C Cawthorne 2,3,7 , M Ali 1 , BA Telfer 1 , M Babur...
The acute promyelocytic leukemia (APL) subtype of AML is treated differently. ; Treatment for AML often needs to start as quickly as possible after it is diagnosed because it can progress very quickly. Sometimes another type of treatment needs to be started even before the chemo has had a chance to work. ; Some people with AML have very high numbers of leukemia cells in their blood when they are first diagnosed, which can cause problems with normal blood circulation. This is called leukostasis, and it needs to be treated right away.
Metastases cause most cancer-related deaths. We investigated the use of hypoxia-selective cytotoxins as adjuvants to radiotherapy in the control of metastatic tumour growth. The NLCQ-1...
IDM-HiDAC = intermediate dose MTX-high-dose cytarabine, Chemo. = multi-agent chemotherapy. Given that ALCL was not recognised as a distinct form of NHL until 1989, most patients prior to...
Transforming Lives Glycobiology-based Therapeutics June 2024 | NASDAQ: GLYC 2 • To the extent that statements contained in this presentation are not descriptions of historical facts, they...
Abstract The management of elderly patients diagnosed with acute myelogenous leukemia (AML) is complicated by high relapse risk and comorbidities that often preclude access to allogeneic...
AML presenting as clinical relapse may be from three underlying sources: (1) chemo-sensitive... doses (HIDAC), and in combination with other therapeutic agents [12,13]. In general, patients...
Abstract Combretastatin A1 (OXi4503) is a dual-function drug with vascular disrupting and cytotoxic properties that has exhibited single-agent anti-leukemia activity in murine xenograft...
Share export Citation Print My folder Superior outcome of patients with favorable-risk acute myeloid leukemia using consolidation with autologous stem cell transplantation. Authors Beyar...
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