The human anti-chimeric antibody (HACA) can develop in patients undergoing autoimmune disease therapy with the drug infliximab. This drug can cause the patient to develop antibodies to the...
monoclonal antibodies has gradually received attention... monoclonal antibodies, the development of associated clinical... monoclonal antibodies (mAbs), against MDR bacteria is one such...
The development of antidrug antibodies, including antirituximab antibodies (ARA) and human antichimeric antibodies (HACA), is reported with rituximab treatment in various diseases. Here we...
Immunomodulatory agents seem to have a protective role against development of HACA or high titers of antibodies. The interval between infusions does not influence the development of HACA.
TmAbs (HACA or HAHA) were reported. However, the methods to detect and quantify such antibodies used in the past have been problematic. Only recently, methods have been developed that have...
antibody (HACA) response in only 1 of 15 patients after a single administration. The purpose... anti-CEA antibodies to allow for better selection of patients for therapy and rational...
antibody [HACA]) has rarely been produced in vivo. We report... developed HACA 6 months after the initial administration of... serum HACA titer, and the number of B lymphocytes in the...
is G, A, V, L, I, P, F, M, W, C, N, Q, S, T, Y, D, E, K, R or H; and ; A polypeptide according to claim 1 comprising an amino acid sequence ; A polypeptide comprising amino acid sequence ; An antagonistic anti-human CD40 monoclonal antibody according to claim 17 or claim 18 comprising an amino acid sequence
남은 셀 복제 Humanization of murine antibodies 최초 승인된 쥐 mAb(OKT3)는 실패 > 면역원성 HAMA 생성 키메라 항체(Chimeric antibody) : (HACA)생성 인간화 항체(Humanized antibody) : (HAHA) 생성 *명명법 : mouse...
Radiolabeled monoclonal antibodies have been studied as a possible treatment for human... antibody (HACA) response. Additionally, chest X-ray, and computed tomography scans of relevant...