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PIEZO2 and perineal mechanosensation are essential for sexual function. - 상세정보 | 인제대학교 의학도서관

Content Provider : MEDLINE Ultimate, 초록 : Despite the potential importance of genital mechanosensation for sexual reproduction, little is known about how perineal touch influences mating. We explored how mechanosensation affords exquisite awareness of the genitals and controls reproduction in mice and humans. Using genetic strategies and in vivo functional imaging, we demonstrated that the mechanosensitive ion channel PIEZO2 (piezo-type mechanosensitive ion channel component 2) is necessary for behavioral sensitivity to perineal touch. PIEZ ...

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of Dental Medicine, Nova Southeastern University, Fort Lauderdale, Florida, USA; 2 Department... 1 Department of Pediatric Dentistry, College of Dental Medicine, Nova Southeastern...

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