mRNA carries protein information from the DNA of a cell’s nucleus to the cell’s cytoplasm. Learn about the function of mRNA.
OBJECTIVECommon variants in FTO (the fat mass– and obesity-associated gene) associate with obesity and type 2 diabetes. The regulation and biological function of FTO mRNA expression in target tissu...
Request PDF | Binary function of mRNA | Since the discovery of messenger RNA (mRNA) over half a century ago, the assumption has always been that the only function of mRNA is to make a... | Find, re...
Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has resulted in the emergence of epitranscriptomics as a research field. The most abundant internal (non-cap) mRNA modi...
Abbreviations ; ASO : antisense oligonucleotide, CoIP : co-immunoprecipitation, DSB : DNA double-strand break, EdU : 5-ethynyl-2′-deoxyuridine, EMSA : electrophoretic mobility shift assay, ENCODE : encyclopedia of DNA elements, ESCC : oesophageal squamous cell carcinoma, FCM : flow cytometry, GAPDH : glyceraldehyde-3-phosphate dehydrogenase, GEPIA : gene expression profiling interactive analysis, IR : ionizing radiation, lncRNAs : long noncoding RNAs, qRT-PCR : quantitative real-time polymerase chain reaction, RACE ...
In yeast, the TREX complex contains the THO transcription elongation complex, which functions in direct cotranscriptional recruitment of the mRNA export proteins Sub2 and Yra1 to nascent transcript...
Recent results have identified a family of Lsm (Like Sm) proteins that are related to the Sm protein family. Seven Lsm proteins form a complex, which interacts with the U6 snRNA and functions in sp...
초록 · It has long been thought that glucocorticoid receptor (GR) functions as a DNA-binding transcription factor in response to its ligand (a glucocorticoid) and thus regulates ... ; 키워드 ; 목차 ; 참고문헌 (0)
The last several years have seen exciting advances in the understanding of the structure and function of higher-order structures of RNA. Expression levels of some specific genes were shown to be di...
Covalently closed circular RNAs (circRNAs) are produced by precursor mRNA back-splicing of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low levels and often exhibi...