Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against Hig

org Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat... On the other hand, a PPARα independent action of fenofibrate also has been reported in various...

Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesi

Fenofibrate, a peroxisome proliferator–activated receptor α (PPARα) agonist, reduces lower limb amputations in patients with type 2 diabetes. The mechanism

[논문]Effects of fenofibrate on lipid parameters in obese rhesus monkeys - 과학기술 지식인프라 ScienceON ....

참고문헌 (51) ; Am. J. Cardiol. Rader 83 30F 1999 10.1016/S0002-9149(99)00270-2 Role of fibrates in the management of hypertriglyceridemia ; Pharmacol. Res. Catapano 4 331 1992 10.1016/1043-6618(92)90232-Z Mode of action of fibrates ; EMBO J. Schoonjans 15 **** **** **.1002/j.1460-2075.1996.tb00918.x PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene ; J. Clin. Invest. Staels 95 705 1995 10.1172/JCI117717 Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase: a potential mechanism for the hypolipidemic action of fibrates

An update on the molecular actions of fenofibrate and its clinical effects on di

Originally considered a lipid-modifying drug, it now appears that multiple mechanisms may underpin the benefit of fenofibrate on diabetic microvascular end points. Fenofibrate regulates the...

Fenofibrate - a potential systemic treatment for diabetic retinopathy? | Sigma-A

Experimental studies investigating the mode of action of fenofibrate were reviewed. The 2 trials included 11 388 patients with type 2 diabetes mellitus, of whom 5701 were treated with...

Role of Fenofibrate Use in Dyslipidemia and Related Comorbidities in the Asian P

Highlights ; This review summarizes the efficacy and safety data of fenofibrate in Asian subjects. ; The cardiovascular benefit of fenofibrate has been proven in certain populations. ; On the contrary, pemafibrate didn’t show cardiovascular benefit in patients with diabetes. ; Both fibrates have distinct characteristics in reduction in LDL-C and apo-B levels.

Fenofibrate: a new treatment for diabetic retinopathy. Molecular mechanisms and - MilliporeSigma

Fenofibrate: a new treatment for diabetic retinopathy. Molecular mechanisms and future perspectives. by Rafael Simó, Sayon Roy, Francine Behar-Cohen, Anthony Keech, Paul Mitchell, Tien Yin Wong. Cu...

Antidyslipidemic action of fenofibrate in dyslipidemic-diabetic hamster model

Fenofibrate is the ligand for PPARalpha subtype that mediates the action of its agonists in lipid metabolism. How fibrate exerts hypolipidemic effect? The mechanism is studied in a newly developed...

Mechanisms of the triglyceride- and cholesterol-lowering effect of fenofibrate i - Article 상세보기-Acces....

In humans, the precise mechanisms of the hypolipidemic action of fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, remain unclear. To gain insight on these mechanisms, we mea...

당뇨성 망막병증에 대한 Fenofibrate와 Statin 병용요법의 효과

Fenofibrate Mechanism of Action. 연구진은 30세 이상 제2형 당뇨병 환자이며 진단 후 90일 이상 연속 스타틴을 투여받은 한국인 2만 3692명과 4만 6223명을 각각 1:2(스타틴+페노파이브레이트 vs....