Improving Paratope and Epitope Prediction by Multi-Modal Contrastive Learning an

Improving Paratope and Epitope Prediction by Multi-Modal Contrastive Learning and Interaction Informativeness Estimation Zhiwei Wang1 † , Yongkang Wang1 † , Wen Zhang1,2 3 ∗ 1 College...

Improving Paratope and Epitope Prediction by Multi-Modal Contrastive Learning an

Improving Paratope and Epitope Prediction by Multi-Modal Contrastive Learning and Interaction Informativeness Estimation Zhiwei Wang 1† Yongkang Wang 1† Wen Zhang 1,2 3∗ 1 College of...

Geometric Epitope and Paratope Prediction | Papers With Code

identifying and neutralizing harmful foreign molecules. In... molecules and emphasize the importance of geometric... (I-GEP) and outer (O-GEP) structures. We incorporate 3D coordinates and...

에피토프 - 미생물학백과 

에피토프(epitope)는 항원(antigen)의 구조에서 항체(antibody), B 림프구 수용체(B cell receptor), 또는, T 림프구 수용체(T cell receptor)와 직접적으로 결합할 수 있는 '항원인식부위'를 의미하며...

Paratope

[2] The uniqueness of a paratope allows it to bind to only one epitope with high affinity and as a result, each B cell can only respond to one epitope. The paratopes on B-cell receptors...

Epitope

[2] Conformational and linear epitopes interact with the paratope based on the 3-D conformation adopted by the epitope, which is determined by the surface features of the involved epitope...

[2405.20668] Improving Paratope and Epitope Prediction by Multi-Modal Contrastiv

Accurately predicting antibody-antigen binding residues, i.e., paratopes and epitopes, is crucial in antibody design. However, existing methods solely focus on uni-modal data (either sequence or st...

Geometric Epitope and Paratope Prediction

Geometric Epitope and Paratope Prediction Marco Pegoraro * 1 Clémentine Dominé * 2 Emanuele Rodolà 1 Petar Veličković 3 Andreea Deac 4 Abstract Antibody-antigen interactions play a...

Recent Progress in Antibody Epitope Prediction

Recent progress in epitope prediction has shown promising results in the development of vaccines and therapeutics against various diseases. However, the overall accuracy and success rate need to be...

Frontiers | Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines

The dynamic interplay between virus and host plays out across many interacting surfaces as virus and host evolve continually in response to one another. In particular, epitope-paratope interactions...