DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria (PubMed:2932432). This DNA polymerase also exhibits 3' to 5' exonuclease activity. T...
Synthesis on Leading and Lagging Strands ; During DNA replication, it contributes in both the leading and lagging strand synthesis. ; It performs a small part in either the leading or the lagging strand synthesis of DNA replication. Thus, it does not have a prominent role in this.
Basis, RNA Polymerase, DNA Polymerase ; 1. Function, Perform transcription of DNA (making RNA copies of the template DNA), Perform replication of DNA (making copies of the parent DNA) ; 2. Product, RNA, DNA ; 3. Cell Cycle Phase, Required in G1 and G2-phases of interphase, Required in S-phase of interphase ; 4. Primer Requirement In Initiation, Need a primer for initiation of transcription, Does not need a primer for initiation of replication ; 5. Base Pairs Used, Adenine, Guanine, Cytosine, and Uracil, Adenine, Guanine, Cytosine, and Thymine ; 6. Error Rate, Very high, Very low ; 7. Proofreading Activity, Absent, Present
lacking DNA Pol I DNA Pol III is the replicative polymerase Loss-of-function mutations in the genes encoding its subunits block DNA replication (dna mutants) Highly processive Multiple...
By function DNA polymerase (DNA-directed DNA polymerase, DdDP) Family A: DNA polymerase I;... Pol α, δ, ε, ζ Family C: DNA polymerase III holoenzyme Family X: Pol β, λ, μ Terminal...
The SuperScript III One-Step RT-PCR System with Platinum Taq DNA Polymerase is designed for the sensitive, reproducible, end-point detection and analysis of RNA molecules by RT-PCR.
coli , including DNA polymerase III (discovered in the 1970s) and DNA polymerases IV and V... Function The main function of DNA polymerase is to synthesize DNA from deoxyribonucleotides...
The SuperScript III One-Step RT-PCR System with Platinum Taq DNA Polymerase is designed for the sensitive, reproducible, end-point detection and analysis of RNA molecules by RT-PCR.
Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex (PubMed:2040637). DNA polymerase III i...
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuc...