Calorie restriction (also known as caloric restriction or energy restriction ) is a dietary regimen that reduces the energy intake from foods and beverages without incurring malnutrition. The possible effect of calorie restriction on body weight management, longevity, and aging-associated ...
Caloric restriction (CR), defined as lessening caloric intake without depriving essential nutrients4 , results in changes in molecular processes that have been associated with aging...
The extension of life span driven by 40% caloric restriction (CR) in rodents causes trade-offs in growth, reproduction, and immune defense that make it difficult to identify therapeutically relevan...
Calorie restriction mimetics (CRM), also known as energy restriction mimetics , are a hypothetical class of dietary supplements or drug candidates that would, in principle, mimic the substantial anti-aging effects that calorie restriction (CR) has on many laboratory animals and humans. CR ...
Rozalyn Anderson, a scientist who studies caloric restriction in monkeys, explains why she thinks energy and metabolism are at the epicenter of the aging process.
Caloric restriction (CR) without malnutrition increases longevity and delays the onset of age-associated disorders in short-lived species, from unicellular organisms to laboratory mice and rats. Th...
The health benefits of chronic caloric restriction resulting in lifespan extension are well established in many short-lived species, but the effects in humans and other primates remain controversia...
The most robust intervention for slowing aging and maintaining health and function in animals is dietary caloric restriction (CR) (1). Although most studies of this phenomenon have been conducted i...
Caloric restriction is a reduction in the amount of calories consumed, relative to an individual’s typical diet or the average diet within a similar population.
Lifelong caloric restriction (CR) may extend life by up to 50% in rodents, with progressively less impact the later in life it is started. This effect is matched by profound impacts on age...