64 Mb PubMed search [3] [4] Wikidata View/Edit Human View/Edit Mouse Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks...
The Bcl-2 family (TC# 1.A.21) consists of a number of evolutionarily-conserved proteins that share Bcl-2 homology (BH) domains. The Bcl-2 family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion. The Bcl-2 family proteins consists of m...
Bcl-2 Family 는 세포사멸(apoptosis)을 조절하는 단백질의 집합으로, 이들 단백질은 세포 생존과 죽음 사이의 균형을 유지하는 중요한 역할을 수행한다. 1980년대 B-세포 림프종의...
수의과대학 김대용 교수 공동연구팀은 공동 연구를 통해서 Bcl-2 family 과 YAP의 병합 억제가 RASA1 및 NF2 결핍이 있는 전이성 위암에서의 합성 치사율을 유도함을 밝히고 그 메커니즘을 규명하였다고 밝혔다.
Caspases, Proto-Oncogene Proteins c-bcl-2, Apoptosis, Truncated BID, Post translational, Mitochondrion, Intrinsic apoptosis, Cell biology, Caspase, Biology, Bcl-2 family, Apoptosome
Bcl-2-related proteins have come to occupy a prominent position in the realm of programmed cell death. Members of this fast-growing family are highly related in one or more specific regions, common...
Bcl-2 family proteins serve as critical regulators of pathways involved in apoptosis, acting to either inhibit or promote cell death. Altered expression of these proteins occurs commonly in human c...
저널정보 한의병리학회 동의생리병리학회지 학술저널 동의생리병리학회지 제22권 제3호 2008.6 630 - 641 (12page) 저자정보 김현중 김홍기 김진영 감철우 박동일
본 제품은 apoptosis에 관여하는 단백질 중에서도 중요한 역할을 하고 있는 human Bcl-2 family 유전자의 cDNA를 구축하는 프라이머와 Positive Control RNA로 구성되어 있다. 이들 primer는 human...
The induction of apoptotic cell death by GMSGBPT was connected with a down-regulation of anti-apoptotic Bcl-2 and Bcl-xL expression, and proteolytic activation of caspase-3 and caspase-9 in A549...