Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide

Our data suggests that the PDE8A-C-Raf complex is a promising therapeutic treatment for B-Raf inhibitor resistant melanoma.

Raf kinase inhibitor protein expression combined with peritoneal involvement and

Raf kinase inhibitor protein expression combined with peritoneal involvement and lymphovascular invasion predicts prognosis in Dukes' B colorectal cancer patients

Raf kinase inhibitor protein

[3] References[edit] ^ a b Odabaei, Golaun; Chatterjee, Devasis; Jazirehi, Ali R.; Goodglick, Lee; Yeung, Kam; Bonavida, Benjamin (2004). "Raf-1 Kinase Inhibitor Protein: Structure...

BRAF (gene)

BRAF , B-RAF1, BRAF1, NS7, RAFB1, B-Raf, B-Raf proto-oncogene, serine/threonine kinase External IDs OMIM : 164757 ; MGI : 88190 ; HomoloGene : 3197 ; GeneCards : BRAF ; OMA :BRAF...

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma | Nature

PLX4032, a small-molecule inhibitor being developed by Plexxikon of California and Roche Pharmaceuticals in New Jersey ( http://go.nature.com/QnVGQx ), selectively targets B-RAFV600E, a mutant form...

melanoma whole-exome sequencing identifies V600E B-RAF amplification-mediated ac

DOI: 10.1038/ncomms1727Received 15 nov 2011 | Accepted 3 Feb 2012 | Published 6 mar 2012 The development of acquired drug resistance hampers the long-term success of B-RAF inhibitor therapy...

Raf-B 억제제 | SCBT - Santa Cruz Biotechnology

Buy Raf-B Inhibitors from Santa Cruz. View and select products within our Raf-B Inhibitors category available for immediate purchase.

The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates a

The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. by J-X Li, J-M Feng, Y Wang, X-H Li, X-X Chen, Y Su, Y-Y Shen, Y Chen, B Xiong, C-...

RAF1 Gene - GeneCards | RAF1 Protein | RAF1 Antibody

GeneCards Symbol: RAF1 · 2 · Raf-1 Proto-Oncogene, Serine/Threonine Kinase · 235 · Raf-1 · 2345 · C-Raf · 235 · CRAF · 235 · RAF Proto-Oncogene Serine/Threonine-Protein Kinase · 34 · V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 · 23 · C-Raf Proto-Oncogene, Serine/Threonine Kinase · 23 · Proto-Oncogene C-RAF · 34 ; EC 2.7.11.1 · 447 · V-Raf-1 Murine Leukemia Viral Oncogene-Like Protein 1 · 3 · Raf Proto-Oncogene Serine/Threonine Protein Kinase · 3 ·...

Raf (Inhibitors Agonists Modulators Antagonists) | TargetMol

Sorafenib ; Regorafenib ; Belvarafenib ; LXH254 is a potent C-Raf and B-Raf inhibitor. PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent to c-Raf-1(Y340D and Y341D mutations). Dabrafenib ; Sulindac sulfide ; GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) . KRPEP-2D acetate ; RAS GTPase inhibitor 1