What is Cell Chemotaxis? ; Definition: Cell chemotaxis refers to the cellular behavior to sense chemotactic factors in the external microenvironment, activate correlative signaling cascades, and move towards the source or high-concentration region of the chemotactic substance. For example, during inflammatory responses, the levels of certain chemotactic factors increase, leading to enhanced migration of specific immune cells. Mechanism: The regulation of cell chemotaxis involves multiple signali...
In this chapter, the authors have provided standardized definitions of cell culture and quantitative biology terms generally employed in assays for HTS and lead optimization. The quantitative biolo...
Assay in the largest biology dictionary online. Free learning resources for students covering all major areas of biology.
저자 : R G Wyatt, H B Greenberg, W D James, A L Pittman, A R Kalica, J Flores, R M Chanock, A Z Kapikian, 학술지정보 : Infection and Immunity · 110p ~ 115p · ISSN 0019-9567 · E-ISSN 1098-5522, 발행정보 : Medline · 1982년, 피인용횟수 : 64, 자료제공처 : MEDLINE®/PubMed® · Crossref, DOI : 10.1128/iai.37.1.110-115.1982, 무료원문 : MEDLINE®/PubMed®, 유료원문 : Crossref, 주제분야 : 의약학 > 면역학, 키워드 : Virus quantification, Virology, Titer, Strain (chemistry), Serotype, Rotavirus, Reoviridae, N ...
The assay: ; Elucidates complex biological systems with distinct clustering of different cell subsets ; Enables interrogation of tens to hundreds of protein markers in a single experiment ; Integrates seamlessly with a catalog of RNA assays—whole transcriptome analyses, targeted RNA assays, TCR and BCR profiling and multiplexing—to serve as a single multiomics solution
Dictionary > Antigen · Antigen ; Antigens may also be classified based on their immune response. As already cited earlier, an immunogen (typically a protein or a polysaccharide) is an antigen that can elicit an immune response by itself, meaning it can trigger a lymphocyte to act against it. In contrast, an antigen that cannot elicit an immune response on its own is referred to as a hapten. It needs another substance — a carrier molecule such as albumin or globulin for instance — before it can trigger an immune response. Compared with an i ...
a. Descriptions of assay formats that are compatible with HTS and determination of SAR, b. Selection and development of optimal assay reagents, c. Optimizations for assay protocols with respect to sensitivity, dynamic range, signal intensity and stability, d. Adaptations of assays for automation and scaling to microtiter plate formats, e. Statistical validation of assay performance parameters, f. Secondary assays for chemical probe validation and SAR refinement, g. Data standards for reporting the results of screening and SAR assays, h. ...
Greene, PhD Newborn Screening and Molecular Biology Branch, Division of Laboratory Sciences NCEH, CDC Tuesday, 9th July 2013 Assay Quality Considerations National Center for Environmental...
참고문헌 (51) ; Proc. Natl. Acad. Sci. USA Boussif O. 7297 92 1996 10.1073/pnas.92.16.7297 A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine Boussif , O. , F. Lezoualc'h , M. A. Zanta , M. D. Mergny , D. Scherman , B. Demeneix , and J. P. Behr . 1996 . A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine . Proc. Natl. Acad. Sci. USA 92 : 7297 - 7301 . ...
What is spatial transcriptomics from 10x Genomics? ; Spatially resolved gene expression, or spatial transcriptomics, is a quantitative readout of either whole transcriptome or targeted gene expression mapped to specific locations in a tissue section, and a proven powerful method to understand cellular composition and activity in the native tissue context. Spatial transcriptomics can be achieved through next-generation sequencing-based approaches, where mRNA is mapped in tissues at the whole tran...