다발성 근염, 피부근염에 특이적인 자기항체로, 항세포질항체의 하나. 히스티딘을 tRNA에 결합시키는 반응을 촉매하는 히스티딜 tRNA합성효소가 인식하는 항원이다. 히스틸딜 tRNA합성효소는 미오신과 아미노산...
In this large cohort of anti-Jo-1 antibody-positive individuals, the incidence of ILD approached 90%. Multiplex ELISA demonstrated disease-specific associations between anti-Jo-1 antibody-positive...
Anti-Jo-1 antibodies in polymyositis or dermatomyositis: evaluation by ELISA using recombinant fusion protein Jo-1 as antigen. by M Nishikai, K Ohya, M Kosaka, K Akiya, T Tojo. British journal of r...
Abstract Of 180 patients with polymyositis/dermatomyositis (PM/DM) seen at the University of Pittsburgh and affiliated hospitals since 1975, 21 of 100 tested positive for the anti-Jo-1 antibody. Si...
and anti-sp100 antibodies. Each of these antibody subtypes binds to different proteins or... La, Jo), or the name of the disease setting in which the antibodies were found (SS-A, SS-B, Scl...
The antinuclear antibody (ANA) is a defining feature of autoimmune connective tissue disease. ANAs are a class of antibodies that bind to cellular components in the nucleus, including proteins, DNA...
Anti-nuclear antibodies (ANAs) are autoantibodies against nuclear substances or other cellular components. ANA tests are used in the diagnostic process to screen patients with suspected...
Myopathological changes in the anti-Jo-1 antibody syndrome include perimysial connective tissue fragmentation and inflammation, with muscle fibre pathology in neighbouring perifascicular regions. M...
Guinea pig Polyclonal GABA antibody. Suitable for ELISA, IHC-FoFr, IHC-P, ICC/IF, IHC-Fr and reacts with Chemical samples. Cited in 27 publications. Immunogen corresponding to Chemical / Small Mole...
서론 ; 자가면역질환은 세포의 핵, 세포질, 또는 표면 등에 존재하는 특정 성분(항원)에 대해 원인을 알 수 없는 하나 또는 두 종류 이상의 자가항체를 생성하는 전신성 면역질환이다. 자가면역질환은 American College of Rheumatology에서 정한 진단기준에 따라 진단하며, 일부 자가면역질환의 경우 특정 자가항체의 유무 확인이 진단에 도움이 되기도 한다. 그러나 자가면역질환은 보통 ...