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The poorly water soluble drug, Indomehacin(IDM) is used as model drug and which is a nonsteroidal,antiinflammatory agent that is used for the treatment of rheumatoid arthritis, ankylosing spondolytis and...
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Description ; BRANCHED MOIETY FOR USE IN CONJUGATES ; The present invention relates to branched moieties and their use in conjugates. ; Background to the invention
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Immunomodulators ; Drug - Immunomodulators · September 2019 · Therapeutic area - Arthritis, Psoriasis, Ankylosing Spondolytis, Ulcerative Colitis, Crohn's Disease, Dermatology · In general, patients must sequentially try and fail a tier 1 product prior to using a tier 2 product and try and fail a tier 1 and a tier 2 product prior to approval of a tier 3 product. All drugs in the immunomodulators PDL category (Table 1) require prior authorization. Providers should fax the completed Immunomo...
Linkers and conjugates Abstract A conjugate comprising a protein or a peptide, a linker and an active agent, wherein the linker comprises the moiety of formula (III): (III) wherein two of...